Statistical study

AG Angela Gentile
JB Julia Bakir
VF Verónica Firpo
EC Enrique V. Casanueva
GE Gabriela Ensinck
SP Santiago Lopez Papucci
ML María F. Lución
HA Hector Abate
AC Aldo Cancellara
FM Fabiana Molina
AG Andrea Gajo Gane
AC Alfredo M. Caruso
AI Alejandro Santillán Iturres
SF Sofía Fossati
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Categorical variables were described as percentages and analyzed through Chi-Squared test with Yates’ correction or Fisher exact test if expected values were <5.

We estimated the number of CP and PP hospitalizations per 10,000 hospital discharges for children ≤ 15 years of age, hospitalized for any cause, per year. Changes in CP and PP rates between the pre-vaccination period 2007–2011 (preVp), the year when PCV13 was introduced (intervention year, 2012) and the post-vaccination period 2013–2014 (postVp) were assessed using the Preventive Fraction in exposed (PFe) formula PFe% = [(Rate preVp–Rate postVp)/ Rate preVp] x 100, with 95% confidence intervals (CIs).

Statistical analysis was performed using Epi Info TM 7 (CDC, Atlanta) and the Open Epi (Open Source Epidemiologic Statistics for Public Health, Version. www.OpenEpi.com, updated on: 2013/04/06). Two-tailed P values <0.05 were considered statistically significant.

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