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Hypertension in Rats Induced by Drinking High-Fructose

JG Jian Guan
MZ Miao Zhao
CH Chao He
XL Xue Li
YL Ying Li
JS Jie Sun
WW Wei Wang
YC Ya-Li Cui
QZ Qing Zhang
BL Bai-Yan Li
GQ Guo-Fen Qiao
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All rats were fed normal laboratory rat chow and water. Rats were maintained on a 12-h light/dark cycle at 25°C and randomly divided into two experimental groups after one week of adaptation. Following a previous report [30], the rats in the control group (Ctrl) continued on a diet of chow and normal water, while the rats in the hypertension group induced by HFD drank water containing 10% (w/v) fructose (Zhiyuan Chemical Co., Binzhou, China) for 7 weeks. After 7 weeks, the HFD rats with an average SBP ≥ 135 mmHg were selected as the HFD models.

Copyright and License information: Shanghai Institutes for Biological Sciences, CAS and Springer Nature Singapore Pte Ltd. ©2018

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