2.1. Cell lines and culture conditions

The human lung cancer cell lines A549 (adenocarcinoma, ATCC CCL‐185), H1975 (adenocarcinoma, ATCC CRL‐5908), H460 (large cell carcinoma, ATCC HTB‐177), H838 (adenocarcinoma, ATCC CRL‐5844) and H1299 (adenocarcinoma, ATCC CRL‐5803), and the foreskin fibroblast cell line Hs68 were purchased from the American Type Culture Collection (ATCC) (Manassas, VA, USA). A549 and Hs68 were grown in DMEM medium (Thermo Fisher Scientific, Rockford, IL, USA), and the other cell lines were grown in RPMI 1640 medium (Thermo Fisher Scientific) supplemented with 10% FBS (v/v), penicillin (100 units/mL) and streptomycin (100 μg/mL). The cells were grown at 37°C in a humidified atmosphere of 5% CO₂ and 95% air.