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Primary outcome measures will be loss in body weight, assessed through body weight, and measured at the highest follow-up time following administration of the intervention.
Secondary outcomes include the total amount of food consumed by the animals; analysis of metabolic parameters, such as total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, glycaemia, inflammatory mediators (interleukin-1 and tumor necrosis factor), mortality for any causes, and any adverse event reported by the authors in any time after mushroom administration.
Copyright and License information: The Author(s). ©2019
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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