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NA Niaz Ali
RB Robina Begum
MF Muhammad Saleh Faisal
AK Aslam Khan
MN Muhammad Nabi
GS Gulfam Shehzadi
SU Shakir Ullah
WA Waqar Ali
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Effects of test concentrations of statins on isolated rabbits’ jejunal preparations were plotted versus respective concentrations of statins as dose repose curves using Graph Pad Prism. Effects were expressed as % of control maximum for spontaneous as well as KCl-induced contractions. For CCRCs, control curves were drawn in Graph Pad Prism. CCRCs were also drawn in presence of respective statins concentrations. Data were analysed using nonlinear regression (curve fit) method with built in equation for sigmoidal dose response using Graph Pad Prism. Two way ANNOVA was used to determine the significances of concentration versus responses at 95 % CI with P < 0.05.

Copyright and License information: The Author(s). ©2016
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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