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The inclusion criteria of our meta-analysis were as follows: (1) case-control studies; (2) investigation of miRNA polymorphisms and RA susceptibility; (3) detailed numbers of alleles and genotypes between cases and controls; (4) full text published in English; (5) control group consistent with Hardy-Weinberg Equilibrium (HWE); and (6) any specific miRNA with at least two case-control studies to evaluate the association between single nuclear polymorphism and RA susceptibility.

The exclusion criteria were as follows: (1) reviews or case reports without controls; (2) no available data reported; and (3) duplicated reports.

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