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Carrageenan Induced Acute Inflammation in Rat Paw Tissues

RA Repally Ayyanna
DA Dasari Ankaiah
VA Venkatesan Arul
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Carrageenan-induced rat paw edema was induced by subplantar injection of 1% carrageenan in sterile saline into the right hind paws of all the groups except control group (Table ​(Table1).1). The acute inflammation induced in hind rat paws by carrageenan was executed as; rat paw thickness was measured before 20 min of carrageenan injection and after carrageenan injection thickness of rat paw was measured at different time intervals (0, 1, 2, 4, and 24 h) by Plethysmometer to examine the inflammation process. The percentage inhibition of paw thickness was calculated using the formula (Solanki et al., 2015).

Experimental grouping of Wistar albino rats.

Copyright and License information:  ©2018 Ayyanna, Ankaiah and Arul.
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