FADD DN or wild-type mice were fed with water charged with 3.0 % (W/V) DSS (dextran sulfate sodium salt, 36–50 kDa, 0216011080, MP Biomedicals) for 5 days and then with normal drinking water for 1 day till sacrificed. Mice given normal water served as control. Body weight of mice was recorded daily. Mice were sacrificed 6 days after DSS exposure. The length of the colons for each group were measured. After washing by PBS, colons tissue were cut and fixed in 4% (v/v) formaldehyde for histological analysis.
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