Dextran sodium sulfate (DSS)-induced colitis

XZ Xuerui Zhang
LH Lina Huo
LS Lulu Song
ZH Zhaoqing Hu
XW Xinran Wang
YH Yuheng Han
YW Ying Wang
PX Peipei Xu
JZ Jing Zhang
ZH Zi-Chun Hua
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FADD DN or wild-type mice were fed with water charged with 3.0 % (W/V) DSS (dextran sulfate sodium salt, 36–50 kDa, 0216011080, MP Biomedicals) for 5 days and then with normal drinking water for 1 day till sacrificed. Mice given normal water served as control. Body weight of mice was recorded daily. Mice were sacrificed 6 days after DSS exposure. The length of the colons for each group were measured. After washing by PBS, colons tissue were cut and fixed in 4% (v/v) formaldehyde for histological analysis.

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