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The quality of evidence for the main outcomes will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation,[23] which contains 4 levels: high level, moderate level, low level, and very low level. Flaws in study design, inconsistency, imprecision, indirectness, and publication bias will be investigated.
Copyright and License information: ©2018 the Author(s). Published by Wolters Kluwer Health, Inc.
This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
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