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Primary outcome measures

IS Ingmar Schäfer
HK Hanna Kaduszkiewicz
CM Christine Mellert
CL Christin Löffler
AM Achim Mortsiefer
AE Annette Ernst
CS Carl-Otto Stolzenbach
BW Birgitt Wiese
HA Heinz-Harald Abholz
MS Martin Scherer
HB Hendrik van den Bussche
AA Attila Altiner
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Our primary outcome measures were the number of medications taken at follow-up (adjusted for the number of medications taken at baseline) and the health-related quality of life at follow-up (adjusted for the health-related quality of life at baseline). Regression coefficients represent the outcome change in the intervention group minus the outcome change in the control group.

We assumed that the number of medications taken by the patient would be reduced as a result of the intervention. A minimum difference of 0.5 medications between both groups was defined as clinically relevant. We assumed that a reduction of medication use would not impair health-related quality of life, that is, we expected that the mean change in health-related quality of life in the intervention group would not be statistically significantly inferior to the mean change in the control group.

Copyright and License information:  ©2018-01-23 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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