Measuring and defining levels of NLR and mGPS

In this study, we assessed NLR and mGPS as systemic inflammation markers. NLR is the neutrophil count divided by the lymphocyte count, and was classified as high (NLR ≥ 3.0) and low (NLR < 3). mGPS was calculated using CRP and serum albumin levels: an elevated CRP levels (> 1 mg/dL) and hypoalbuminemia (< 3.5 g/dL) was designated as 2 points, elevated CRP and normal albumin levels denoted 1 point, and CRP levels ≤ 1 mg/dL with normal albumin levels indicated 0 points. mGPS was classified into two groups: high (a score of 2) and low (a score of 0 or 1). There were four categories of change in NLR and mGPS values between the prechemotherapy and postchemotherapy periods: low to low, high to low, low to high, and high to high; these were designated as A, B, C, and D, respectively.