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Case Series

LC Laura Capelli
AG Andrea Casadei Gardini
ES Emanuela Scarpi
GF Giovanni Luca Frassineti
LS Luca Saragoni
MP Maurizio Puccetti
MS Mario Scartozzi
MG Massimo Giannini
ST Stefano Tamberi
JC Jody Corbelli
PU Paola Ulivi
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We analyzed a case series of 50 consecutive SCAC patients treated with chemotherapy and radiotherapy at Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS in Meldola and at the Medical Oncology Units of Faenza, Ravenna and Macerata Hospitals from March 2001 to August 2012, for whom histological material was available. Forty-eight patients received the Nigro scheme with standard dosages19, while the remaining 2 patients underwent treatment with cisplatin plus 5-fluorouracil. This case series was previously characterized by our group for HPV infection, KRAS (exons 2–4), BRAF (exons 11 and 15) and PIK3CA (exons 9 and 20) status15.

The study protocol was reviewed and approved by the Medical Scientific Committee of IRST IRCCS, and written informed consent was obtained from patients or from their next of kin for the use of biological samples for research purposes. In addition, the experiments in this study were conducted in accordance with approved guidelines and regulations.

Copyright and License information:  ©2016, The Author(s)
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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