From the three-coloured images generated by the present image analysis, volumes defined as resorbed and formed bone (mm3) were isolated and expressed as a percentage of the baseline bone volume (BV). For the threshold values ranging from 200 to 275 mg HA/cm3, the ex vivo least-detectable bone remodelling (mean ± SD, %) was determined by averaging the percentage of resorbed and formed bone over all cadaveric forearms. The in vivo least-detectable bone remodelling (mean ± SD, %) was determined for all images and then for each image quality group individually. Finally, age-related bone remodelling (mean ± SD, %) in postmenopausal women was determined independently from image quality and at 2, 4, and 6 years follow-up.
Do you have any questions about this protocol?
Post your question to gather feedback from the community. We will also invite the authors of this article to respond.