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2.3. Molecular Methods for Estimation of Phasing

LH Linda M. Henricks
JS Jan H. M. Schellens
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In regard to the size of the DPYD gene, the location of the variants, and the material available (DNA, RNA) from the patients, three molecular methods to determine the phasing of the variants could be used in this study. In four patients, we could execute one or more of these methods. These methods are explained and illustrated in the supplementary material (Figure S1). Details on these techniques have been published elsewhere [29,30,31].

Copyright and License information:  ©2018 by the authors.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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