Summary of more and less preferred treatments

For the primary outcome, we developed a system to summarize the results, establishing different groups of interventions (from the best to the worst interventions groups) based on the effect estimates obtained from the NMA, their associated evidence certainty, and their SUCRA (ranking) values. First, we separated moderate-to-high quality (which we define as: high certainty) and low-to-very-low (which we defined as: low certainty) bodies of evidence (based on the GRADE). Then, within each group, we separated treatments based on the magnitude of effect estimates (i.e., based on the magnitude of the effect on reduction in diarrhea duration), as follows: 1)Amongst the best interventions: based on the effect estimates these interventions were all better than STND (they had the largest reduction in diarrhea duration), and also superior to interventions that at the same time, were better than STND (i.e., credible interval of estimates between interventions from group 2 excluded the null value); 2)Inferior to the best but better than the worst interventions: based on the effect estimates these interventions were superior to STND (credible interval of estimates between the intervention and STND excluded the null value), but inferior to interventions from group (1); and 3)Amongst the worst interventions: these interventions showed no differences in effect estimates when compared to STND).