2.3. Statistical Analysis

Statistical data analysis was carried out using the STATA software (version 13.0, STATACORP LP, College Station, TX, USA). Qualitative variables were described in percentages, and quantitative variables were described by mean with standard deviation or by median with interquartile range. Intragroup serial comparisons of categorical variables at baseline and month 3 were carried out using the Wilcoxon signed-rank test. Intragroup serial comparisons of continuous variables at baseline and follow-up were carried out using the Exact McNemar signification probability test. Intergroup serial comparisons were carried out using Mann–Whitney test for categorical variables and Pearson's chi-square for continuous variables. Cohen's kappa coefficient was used to measure the interuser agreement for qualitative items on OCTA at baseline and follow-up. The chosen level of statistical significance was P < 0.05.