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PubMed, Embase, Web of Science, and CENTRAL databases were searched systematically, as well as the references of eligible studies and recent reviews from inception to December 31, 2016. The keywords and corresponding Medical Subject Headings (Mesh) were as follows: “adenosine”, “anisodamine”, “calcium channel blockers”, “diltiazem”, “verapamil”, “nicorandil”, “nitroprusside”, “urapidil”, “vasodilator agents”, “intracoronary”, “myocardial infarction”, and “percutaneous coronary intervention”. No limits regarding language and publication type were applied.

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