To test the effects of IAC ablation, together with and without the application of PVI, we used the following approach. For each set-up, AF was analysed (as detailed in Arrhythmia Analysis section) 3 s post-initiation, for 2 s. At 5 s post-initiation, ablation of IACs or PVI was applied. Arrhythmia dynamics were analysed for 2 s post-ablation. In the case of combined PVI and IAC ablation, IAC ablation was applied 2 s post-PVI, and again the arrhythmia dynamics were assessed for a further 2 s.
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