Complete Freund’s adjuvant-induced arthritis in rats

MM Muhammad Majid
BN Bakht Nasir
SZ Syeda Saniya Zahra
MK Muhammad Rashid Khan
BM Bushra Mirza
IH Ihsan-ul Haq
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Arthritic rat model was prepared by using Complete Freund’s adjuvant (heated-killed Mycobacterium tuberculosis in 1 ml of liquid paraffin at 10 mg/kg). Briefly, 200 μl of CFA emulsion was injected subcutaneously at the base of the tail of rat under anesthesia [36]. Study plan was sub-divided in following two schemes.

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