Design

This was a prospective study of quality of life in OSMF patients. The study was conducted in Bhabha College of Dental Sciences, Bhopal, India, during one complete calendar year from April 2015 to March 2016. Bhabha College of Dental Sciences is one of the reputed dental teaching hospitals in Central India, affiliated to Madhya Pradesh University of Health Sciences. We identified 100 OSMF patients attending the dental outpatient department (OPD) who were interviewed at this baseline stage. A detailed case history of all patients was recorded and diagnosis of OSMF was made by clinical examination. The one hundred oral submucous fibrosis patients were divided into two groups, Group A and Group B. Group A (n=50) received oral Spirulina capsule 500 mg twice daily. Group B (n=50) received oral Spirulina capsule 500 mg twice daily along with topical triamcinolone acetonide 0.1%. There were no restrictions on patient selection with regard to history of areca nut use, disease stage and demographic characteristics. First follow-up was scheduled one month after initial treatment and the subsequent assessments were made two and three months after initial treatment. The ethical committee of the institute approved the study and treatment was carried out with the patients’ permissions.