Spinal Nerve Ligation Model

WZ Wei Zhang
YB Yang Bai
YQ Yu Qiao
JW Jian Wang
ML Meng-Ying Li
JW Jing-Wen Wang
NJ Na Jia
TC Tao Chen
YL Yun-Qing Li
AW Ai-Dong Wen
request Request a Protocol
ask Ask a question
Favorite

SNL model was performed according to our previous study (Wang W. et al., 2012). First, the rats were anesthetized with intraperitoneal injection of chloral hydrate (280 mg/kg). Next, the transverse process of the sixth left lumbar was cut off to expose the L4 and L5 spinal nerves. Subsequently, the L5 spinal nerve was separated and ligated by 6–0 silk sutures, and the incision was closed layer by layer. Rats in the sham group received the same procedures except for nerve ligation.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A