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The Complete Freund’s Adjuvant (CFA)-Induced Arthritis Model
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The CFA-induced mouse arthritis was induced by intra-articular injection of 20 µl of CFA (1 mg/ml, Sigma, #F5881, USA) (25, 26). NC group mice were received the same volume of PBS as controls. 24 h later, mice were injected intramuscularly with 20 µg DsCystatin or PBS (as controls) every 2 days. Ankle thickness was measured every 2 days. At day 21 following the CFA injections, mice were sacrificed and joints were dissected for pathological analysis.
Copyright and License information: ©2018 Sun, Wang, Pan, Wu, Wang and Dai.
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