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Conditioned taste aversion study
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Lean mice were trained to consume their daily water requirements over 1 h, then given access to saccharin-sweetened Kool-Aid, followed immediately by IP injection of a potentially aversive stimulus (vehicle, agonist, or LiCl 0.15 M in a volume equivalent to 2% body weight as positive control). After 24 h recovery, mice were given a free choice of water or Kool-Aid. Taste preference was calculated as Kool-Aid/total fluid consumed.
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