oPOSSUM59 single site analysis was applied with the following options: 0.40 conservation cutoff, 85% matrix match threshold, sequences of −5,000 to 5,000 bp from the transcription start site, and all genes in the oPOSSUM database. Shared common genes with a p-value < 0.1 from the differential analysis in the two cell lines were used as an input to be searched against the Jaspar database.
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