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Contrast enhanced Magnetic Resonance Imaging (MRI)

YL Yuriy V. Loskutov
CG Caryn L. Griffin
KM Kristina M. Marinak
AB Andrey Bobko
NM Naira V. Margaryan
WG Werner J. Geldenhuys
JS Jann N. Sarkaria
EP Elena N. Pugacheva
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To visualize the intracranial tumors, mice were intraperitoneally injected with gadolinium-DTPA (contrast reagent, BioPAL) to a final concentration of 2mmol/kg (55), and imaged with a compact MRI system (ICON, Bruker). Images were taken with T1 weighted RARE sequence (echo time: 26.23ms; repetition time 1984.158ms; averages: 8; rare factor: 6). Overall time of scan was 25min and final resolution was 0.125mm for all axes. Stack images were reconstructed and analyzed using ImageJ (NIH).

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