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Animal experiments

TO Tamás Oláh
JR Jan Reinhard
LG Liang Gao
LG Lars K. H. Goebel
HM Henning Madry
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Nine healthy Merino ewes (mean body weight, 70 ± 20 kg; age ~1.5 years old) underwent open transection of the anterior root of the medial meniscus on their right knees53 for an unrelated study. Their left knees served as unoperated control. All animal experiments were conducted in agreement with the national legislation on protection of animals and the National Institutes of Health (NIH) Guidelines for the Care and Use of Laboratory Animals (NIH Publication 85–23, Rev 1985) and were approved by the Saarland University Animal Committee according to German guidelines. Animals were sacrificed at 6 months postoperatively. Tibial plateaus were harvested and used for micro-CT evaluations. Artefacts visible on some of the images are related to experiments not described here, and they are not affecting the reliability of the present study.

Copyright and License information: The Author(s) ©2017
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