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As a plugin to Cytoscape, Molecular Complex Detection (MCODE) (17) was used to detect densely connected regions from the PPI network with the following cutoff values: Degree cutoff, 2; node score cutoff, 0.2; k-core, 2; and maximum depth, 100. Subsequently, based on modules selected from the PPI network, functional enrichment analysis was performed with the criterion of P<0.05.
Copyright and License information: ©2017, Spandidos Publications
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