Bioluminescence imaging (BLI)

QZ Qi Zhang
RL Ruichao Li
XC Xu Chen
SL Sang Beom Lee
JP Jing Pan
DX Donghai Xiong
JH Jiaqi Hu
MM Mark Steven Miller
ES Eva Szabo
RL Ronald A. Lubet
YW Yian Wang
MY Ming You
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Briefly, tumors were imaged 10 min post 200 μL (15 mg/mL) intraperitoneal injection of D-luciferin (Xenogen Corporation). Isoflurane anesthetized mice were imaged at indicated time points using the Lumina IVIS-100 in vivo Imaging System (Xenogen Corporation). Regions of interest were created and measured as area flux, defined by radiance (photons per second per square centimeter per steradian) according to the manufacturer's calibration (Xenogen Corporation) [19].

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