Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Construction of interaction network based on pathway

HZ Haocong Zhang
YW Yan Wang
request Request a Protocol
ask Ask a question
Favorite

Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) can provide uniquely comprehensive coverage and ease of access to both experimental as well as predicted interaction information that is denoted with a confidence score [21]. In the present study, STRING was used to construct an interaction network of the DEGs significantly enriched in pathways, and a score threshold of 0.4 was adopted. The resulting network was visualized using Cytoscape [22].

Copyright and License information: The Author(s). ©2016
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

0/150

tip Tips for asking effective questions

+ Description

Write a detailed description. Include all information that will help others answer your question including experimental processes, conditions, and relevant images.

post Post a Question
0 Q&A