In vitro toxicity assay was used to confirm the resistance level of cisplatin‐resistant HONE1 cell line. Relative cell viability of cells after cisplatin treatment was determined by in vitro Toxicology Assay Kit Sulforhodamine B assay (TOX6 from Sigma‐Aldrich, St. Louis, MO) according to manufacturer's protocol. The percentage of viability of cells was calculated by number of cisplatin‐treated viable cells / number of viable cells of untreated control.
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