Mutations in CENPI were identified as described [56, 57]. The results from five studies were included in this analysis: Broad, Nature 2012; British Columbia, Nature 2012; Sanger, Nature 2012; TCGA, Provisional; METABRIC, Nature 2012 & Nat Commun 2016, as referenced [56, 57]. The total sample numbers with the number of mutated samples were 103 samples/0 CENPI mutations, 65/1, 100/1, 1105/5, 2399/0, respectively. The functional impact of the mutations on the protein was predicted as described [26].
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