Statistical analysis was performed using GraphPad Prism 5 software. All values were presented as mean ± standard deviation (SD). * P<0.05, ** P<0.01, *** P<0.001 were considered to be statistically significant. Student’s t test (two-tailed) or ANOVA (Dunnett’s multiple comparison post-test) were used to analyze the difference between drug treatment groups and control groups. Survival analyses were performed using Kaplan-Meier method and two-sided log-rank tests.
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