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Four CAPS patients positive for mutations of the NLPR3 gene and four age-matched healthy controls were studied in parallel. Blood samples were taken after informed consent by patients or parents, approved by the ‘G Gaslini' Ethical Board,50 and monocytes stimulated as above.
Copyright and License information: ©2016 The Author(s)
Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
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