2.8. Bioinformatic analysis

SP Sofia Pavanello
MB Matteo Bonzini
LA Laura Angelici
VM Valeria Motta
LP Laura Pergoli
MH Mirjam Hoxha
LC Laura Cantone
PC Pesatori Angela Cecilia
AP Apostoli Pietro
TA Tripodi Armando
BA Baccarelli Andrea
VB Valentina Bollati
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A biological interpretation of EVmiRNAs expression data was done using Ingenuity Pathway Analysis (IPA) software as previously described (Bollati et al. 2015). IPA was queried for target mRNAs that were experimentally observed or predicted with a high confidence level and a Core Analysis was run using the target gene lists.

The top five networks, functions and molecules for ontologies that are related to inflammatory processes, immune functions and processes related to cardiovascular system development were considered.

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