Statistics

A Grubb’s outlier test was performed on data sets to determine any outliers in results from each genotype. After confirmation of no detection of DAT protein in the DAT −/−, DAT expression between the WT and DAT-HET was evaluated with a one-tailed unpaired t test, on the hypothesis that DAT expression has been previously reported to decrease in the DAT-HET genotype.⁵⁷ For all other statistical analyses, a one-way ANOVA was run on each dependent measure obtained from the 3 groups followed by a Holm–Sidak’s multiple comparisons post hoc test to compare DA, DA turnover, and DAT and TH expression and TH phosphorylation differences among the three groups. Significance was set at p < 0.05.