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NAFLD Activity Score (NAS) for disease severity
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The NAS is a valid and reliable histological scoring tool that was developed for the purpose of numerically rating the progression of NAFLD in patient liver biopsies [20]. The scoring includes measurement of steatosis grade (0-no steatosis, 1 - <50% steatosis, 2 - > 50% steatosis, 3 - >50% steatosis + microvesicular steatosis), hepatocyte ballooning (0- none, 1- <66%, 2- >66% hepatocyte involvement) and inflammation (0-no foci, 1- <2 foci, 2–2–4 foci, 3- +4 foci). A score of 4 or above signifies the development of NASH [21].
Copyright and License information: ©2016 Reid et al
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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