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The gene expression profile of GSE3298 [3, 14], which describes mRNA expression in the rat proximal femoral growth plate after mid-shaft fracture, was derived from the Gene Expression Omnibus (GEO, http://ncbi.nlm.nih.gov/geo/) database based on the GPL1355 Affy metrix Rat Genome 230 2.0 Array platform (Santa Clara, CA, USA). A total of 16 femoral growth plate samples were used for analysis, including nine samples without fracture and seven fracture samples for seven time points: 1 day, 3 days, 1 week, 2 weeks, 3 weeks, 4 weeks, and 6 weeks, after mid-shaft fracture.

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