Memorial Sloan-Kettering Cancer Centre score predicts survival based on clinical and laboratory data in metastatic RCC patients. It is a combination of: (1) performance status (Karnofsky score)<80%, (2) time from diagnosis to systemic treatment<12 months, (3) haemoglobin less than the lower limit of normal, (4) lactate dehydrogenase>1.5 × upper limit of normal, (5) corrected calcium>10 mg dl−1 (2.5 mmol l−1). Score 0, 1–2 or ⩾3 corresponding respectively to Good, Intermediate or Bad Risk Group (Motzer et al, 1999).
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