Animals

Kcna1-null mice were bred at the Barrow Neurological Institute (Phoenix, Arizona) vivarium. Mice were born and reared in a quiet, temperature-controlled room and entrained to a 12 hour light–dark cycle; lights on at zeitgeber time (ZT) 00:00. Tail clips were taken at P13–P15 and sent to Transnetyx Inc. for genotyping (Cordova, TN, U.S.A.). All protocols were in accordance with National Institutes of Health (NIH) guidelines and approved by Barrow Institutional Animal Care and Use Committee.