Generation of capivasertib resistant cell lines (capiR)

VC Valentina Cutano
MC Ming Li Chia
EW Eleanor M Wigmore
LH Lorna Hopcroft
SW Stuart C Williamson
AC Amanda L Christie
BW Brandon Willis
JK James Kerr
JA Jenny Ashforth
RF Rhys Fox
SD Sophie D’Arcy
LB Lauren Bradshaw
CB Catherine Blaker
CE Cath Eberlein
LM Lambert Montava-Garriga
EB Elza C de Bruin
SC Susan E Critchlow
KB Kevin M Brindle
SB Simon T Barry
SR Susana Ros
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To generate resistant cell populations parallel cultures of parental cell lines were exposed to escalating concentrations of capivasertib over 6 months up to a final dose of 10 μM which generated 2 T47D (capiR R1, R2) and 3 MCF7 capiR cell pools (capiR R1, R2, R3).

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