Measurement of platelet cAMP levels

RA Riyaad Aungraheeta
AC Alexandra Conibear
MB Mark Butler
EK Eamonn Kelly
SN Sven Nylander
AM Andrew Mumford
SM Stuart J. Mundell
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Washed platelets were stimulated in the presence of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine (IMBX) (100 µM), and drug-induced changes in platelet cyclic adenosine monophosphate (cAMP) levels were assessed as described before.23

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