2.4. Lentiviral shRNA

The sequences of CK1ε, SIAH1 (Human), Siah1α (Mouse) shRNAs were as follows: shCK1ε‐1: sense CCGGCCAGTGTTTGCTTAGTGTCTTCTCGAGAAGACACTAAGCAAACACTGGTTTTTG, anti‐sense AATTCAAAAACCAGTGTTTGCTTAGTGTCTTCTCGAGAAGACACTAAGCAAACACTGG; shCK1ε‐2: sense CCGGCTCTTACCTACGTCAGCTCTTCTCGAGAAGAGCTGACGTAGGTAAGAGTTTTTG, anti‐sense AATTCAAAAACTCTTACCTACGTCAGCTCTTCTCGAGAAGAGCTGACGTAGGTAAGAG; and shSIAH1: sense CCGGGAAGCGACTCCTCGATCTATTCTCGAGAATAGATCGAGGAGTCGCTTCTTTTTG, anti‐sense AATTCAAAAAGAAGCGACTCCTCGATCTATTCTCGAGAATAGATCGAGGAGTCGCTTC, shSiah1α: sense CCGGGCATCAGCACAAGTCCATTACCTCGAGGTAATGGACTTGTGCTGATGCTTTTTG, anti‐sense AATTCAAAAAGCATCAGCACAAGTCCATTACCTCGAGGTAATGGACTTGTGCTGATGC. For infection with lentivirus, the cells were cultured with lentiviral solution for 24 h in the presence of 4 μg·mL⁻¹ polybrene (Merck, Darmstadt, Germany).