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To assess the volume of the thymus, we used methods described elsewhere (Le Voyer et al., 2023; Materna et al., 2024). Briefly, the thymus was measured in three planes: (i) thickness, (ii) width in the axial plane through the aortic arch, and (iii) greatest height in a coronal or sagittal oblique plane. Thymic volume was estimated with the following formula: thickness × width × height. Detailed information about the patients and the age-matched controls is provided in Table S6.
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