Study Design

MG McLeod Frampton Gwynette
DL Danielle W Lowe
EH Erin A Henneberry
MW Melanie Gail Wiley
HA Hussam Alsarraf
SR Sarah Brice Russo
JJ Jane E. Joseph
PS Philipp M. Summers
LL Laura Lohnes
GS Gregory L. Sahlem
MG Mark S. George
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Prospective participants completed an initial assessment via a structured psychiatric clinical interview, IQ testing, and review of documentation of prior diagnostic testing for ASD, MDD, or intellectual disabilities. Female participants were given a pregnancy test. Once eligibility was confirmed and consent given, participants and designated informants (usually a parent) filled out standardized clinical scales for the participant’s baseline MDD and ASD symptom burden. Participants were then treated with twenty-five sessions of rTMS as described below. Allowances were made for missed appointments or holidays, in order for each person to receive 25 treatment sessions within 6 calendar weeks. After completion of the rTMS sessions, post-treatment clinical scales were completed. One-month and three-month follow-up clinical scales were sought from participants and their informants.

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