Catalytic selective hydrogenation of 5-chloroquinolines catalyzed by various catalysts

Xiao-Jue Bai; Caoyu Yang; Zhiyong Tang

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Catalytic selective hydrogenation of 5-chloroquinolines catalyzed by various catalysts

XB Xiao-Jue Bai

CY Caoyu Yang

ZT Zhiyong Tang

This method is extracted from research article: Nat Commun, Jul 2024

Enabling long-distance hydrogen spillover in nonreducible metal-organic frameworks for catalytic reaction

DOI: 10.1038/s41467-024-50706-1

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In a typical procedure, each catalyst containing the same amount of Pt NPs (0.002 mmol) was dispersed in 2 mL isopropanol solution, and then 81.8 mg 5-chloroquinoline (0.5 mmol) was added to the above solution. Subsequently, the solution was transferred into a Teflon-lined stainless-steel autoclave, the autoclave was purged with H2 for 4 times, and the final H2 pressure of the autoclave was set at 2 MPa. During the catalytic process, the reaction solution was magnetically stirred at the speed of 600 rpm at 100 °C for 120 min. After that, the catalysts were separated by centrifugation, and washed with ethanol for reusing; while the obtained reaction solution was filtered through a filter membrane (0.22 μm), and then was analyzed by gas chromatography (GC, Shimadzu, GC-2010 Plus, column: Rtx-5, 30 m × 0.25 mm × 0.25 µm).

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