For the seven different MCID values calculated for each PRO instrument, we determined whether the distribution of values exhibited a normal or skewed distribution. For all three instruments, a positively skewed distribution of MCID values was present. We calculated the median MCID value as well as the interquartile range (IQR) of the combined anchor-based and distribution-based estimates. Because of the skewed distribution, we report the median as the measure of central tendency and use the IQR to represent error (rather than the mean with a confidence interval for a normal distribution).
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