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The present study was approved by the Ethics and Human Research Committee of the Universitat de València (UV), with registration number H148473676706. Inclusion criteria were over 18 years of age, one or more teeth that responded negatively to cold sensitivity tests (negative vitality was confirmed by the absence of bleeding after opening), no antibiotics in the last month, no communication between the buccal environment and the pulp chamber. Teeth with periodontal pocket >4 mm, mobility or root fracture were excluded.
Copyright and License information: ©2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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