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Sensitivity analyses

AR Amy Ronaldson
JT Jorge Arias de la Torre
MA Mark Ashworth
AH Anna L. Hansell
MH Matthew Hotopf
IM Ian Mudway
RS Rob Stewart
AD Alex Dregan
IB Ioannis Bakolis
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Three sensitivity analyses were performed:

To address misclassification and uncertainties over diagnosis and exposure we restricted our analyses to those who completed the baseline assessment in 2010, so that exposure and outcome were measured in the same year.

To account for possible clustering of individuals at assessment centers, we examined associations using mixed-effects ordered logistic regression where exposure to air pollution was considered at level one (fixed effects) and assessment center was considered at level 2 (random effects).

We ran two-pollutant models where each pollutant was included as a covariate with every other pollutant in order to examine co-pollutant confounding.

Copyright and License information:  ©2022 Ronaldson, Arias de la Torre, Ashworth, Hansell, Hotopf, Mudway, Stewart, Dregan and Bakolis.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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