Differential expression analysis, survival analysis and biological function enrichment analysis of lncRNA PVT1

WC Wei Cao
WZ Weiguo Zhou
ML Mengying Li
ZZ Zehua Zhang
XZ Xun Zhang
KY Kang Yang
SY Shiyi Yang
GC Guodong Cao
BC Bo Chen
MX Maoming Xiong
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The ggpubr software package was used to analyze the differential expression of lncRNA plasmacytoma variant translocation 1 (PVT1), and further found out the correlation between lncRNA PVT1 and the clinical features of patients with GC. Then, the K-M survival curve of PVT1 was drawn by survival package and survivminer package. Finally, Gene Set Enrichment Analysis (GSEA), GO and KEGG enrichment analysis were used to explore the biological function of PVT1. The thresholds of the former were Nominal p-value < 0.05 and FDR Q-value < 0.25, and the thresholds of the latter two were P < 0.05.

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