Statistical Analysis

GraphPad Prism 9 (GraphPad Software, CA) was used for statistical analysis and data represented as the mean ± standard error of the mean. For platelet adhesion in vivo, and platelet counts in blood taken from mice following in vivo cremaster studies, comparisons by genotype within each test group (e.g., CTH vs. saline) were done with a Student’s t-test. For platelet aggregation studies, comparison of final platelet aggregation was done via a two-way analysis of variance (ANOVA) followed by Tukey’s multiple comparisons post-hoc test. A p-value of < 0.05 was considered statistically significant.